Table 1. Incidence of PTEN and PIK3CA mutations in human cancers.

Primary tumor tissue	Percentage of tumors with mutation/number of samples
	PIK3CA		PTEN
	%	#	%	#
Prostate	29	7	14	371
Breast	27	987	6	561
Endometrium	23	199	38	1467
Colon	15	1128	9	344
Urinary tract	17	162	9	142
Upper aerodigestive tract	10	229	4	529
Ovary	8	670	8	574
Stomach	8	362	5	446
Liver	7	253	5	354
Esophagus	7	124	1	94
Pancreas	6	66	1	67
Central nervous system	5	808	20	2758
Hematopoietic and lymphoid tissue	4	510	6	866
Lung	3	537	8	548
Skin	3	149	17	555
Thyroid	2	186	5	591