Table 3.
Coexpression of LepR and Phospho-STAT3 in the CNS
| Nucleus | Number of cells pSTAT3/LacZ+ | Percent of LacZ cells that were pSTAT3/LacZ+ |
|---|---|---|
| Intercalate nucleus | 37 ± 12 | 26 ± 5 |
| Nucleus of the solitary tract | 378 ± 70 | 72 ± 12 |
| Parabrachial nucleus | 122 ± 45 | 20 ± 10 |
| Dorsal raphe | 305 ± 125 | 75 ± 13 |
| Periaqueductal gray ventral | 323 ± 45 | 97 ± 4 |
| Periaqueductal gray dorsal/lateral | 125 ± 90 | 15 ± 8 |
| Periaqueductal gray | 142 ± 15 | 42 ± 10 |
| Posterior hypothalamic area | 12 ±2 | 97 ± 5 |
| Ventral premammilary nucleus | 1200 ± 145 | 94 ± 3 |
| Arcuate nucleus | 5360 ± 200 | 98 ± 1 |
| Ventral medial nucleus | 185 ± 30 | 94 ± 5 |
| Dorsal medial nucleus ventral | 778 ± 100 | 94 ± 3 |
| Dorsal medial nucleus dorsal | 218 ± 40 | 23 ± 6 |
| Lateral hypothalamic area | 195 ± 100 | 29 ± 11 |
| Periventricular nucleus | 20 ±1 | 90 ± 14 |
| Medial preoptic area | 613 ± 115 | 86 ± 5 |
Quantitation of pSTAT3 and LepRb Cre-activated lacZ coexpression in the CNS. Limited nuclei demonstrated coexpression of both markers. Cell counts were presented as the number of double-positive cells per nuclei (average of 3 brains ± SEM). The percentage of all LacZ-positive cells within the nuclei that were also double-positive is presented in the right-most column.