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. 2009 Jun 18;15(9-10):307–315. doi: 10.2119/molmed.2009.00025

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Copyright 2009, The Feinstein Institute for Medical Research

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rAAV-CD151 transfection enhances myocardial perfusion and reduces ischemia. (A) ¹³N-NH₃ PET images of the control group. (B–D) ¹³N-NH₃ PET images of the rAAV-GFP, rAAV-CD151, and rAAV-antiCD151 groups in three axes. (B) Short axis images. (C) Vertical axis images. (D) Horizontal axis images. The control group exhibited no detectable defect. At 3 d after viral transduction, three viral transduced groups displayed similar myocardial perfusion. At 8 wks after viral administration, the rAAV-CD151 group exhibited significantly improved myocardial perfusion compared with the rAAV-GFP group. In contrast, rAAV-antiCD151 group revealed decreased perfusion.