Figure 6. Protection of guinea pigs against anthrax infection.

(A) Female Hartley guinea pigs (n = 6 for each group) were i.m. administered with the indicated doses of cAb 29, followed by s.c. challenge with 40LD₅₀ of B. anthracis Vollum spores 14 hrs later. (B) 30 days after the first challenge, surviving animals from groups 20 and 10+10 mg/kg were re-challenged with the same dose (40LD₅₀), and survival was then monitored for another 14 days.