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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: J Am Chem Soc. 2006 Mar 8;128(9):2893–2901. doi: 10.1021/ja057489m

Table 1.

(a)

graphic file with name nihms-123265-t0016.jpg
entry ligand dr(b) Isolated Yield (7 + 8)
1 P[(p-MeO)C6H4]3 8:1 54%
2 PPh3 5:1 27%
3 P(o-tol)3 2:1 35%
4 PCy3 2:1 48%
5 DPE-Phos 1:1 49%
6 DPPE 1:2 46%
7 DPP-Benzene 1:2 44%
8 (±)-BINAP 1:18 60%
(a)

Conditions: 1.0 equiv 6, 2.0 equiv NaOtBu, 1 mol % Pd2(dba)3, 4 mol % ligand (monophosphines) or 2 mol % ligand (bis-phosphines), toluene (0.1 M), 105 °C, 3-8 h.

(b)

Diastereoselectivities were determined by GC and/or 1H NMR analysis of crude reaction mixtures.