Fig. 3.

Structural similarity of the N protein in the P_CTD-bound and unbound states. Two molecules of the P_CTD-bound N290 molecules are colored red and green. Two additional molecules (colored gray) of the previously determined structure N290 (PDB accession ID: 2qvj) were superimposed upon the current complex structure. The main dissimilarity between the structures is observed in the conformation of the C loops (acknowledged with arrows). This corresponds to the site of P_CTD binding. The models are rotated 180° with respect to Fig. 1; in this case, looking from the exterior of the protein rather than the RNA cavity face of N.