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. 2009 Jul;11(4):290–297. doi: 10.2353/jmoldx.2009.080124

Figure 4.

Figure 4

Specific examples of LOH in pancreatic adenocarcinoma samples. Top: Chromosomal region of chromosome 10 that harbors the PTEN tumor gene (coordinates indicated to the right) in unsorted and sorted fractions from three separate tumors. Heatmap colors represent the probability that a stretch of homozygous SNPs could arise by chance as indicated in the key. Bottom: Region of chromosome 9 that harbors the CDK2NA locus. Tumor 2 shows LOH at the PTEN and CDK2NA loci specifically in the neoplastic fraction but not in unsorted tissue or the stromal fraction.