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. 2009 Jul;11(4):290–297. doi: 10.2353/jmoldx.2009.080124

Figure 6.

Figure 6

Sequence analysis of the KRAS locus in sorted pancreatic adenocarcinoma tissue. Upper sequence traces show analysis of a region of exon 2 in KRAS with nucleotide change predicted to cause a G12D amino acid substitution apparent in the neoplastic fraction but not the stromal fraction. Lower sequence traces show analysis of a region of exon 3 in KRAS with nucleotide change predicted to cause a Q61R amino acid substitution apparent in the tumor and stromal fractions but substantially enriched in the tumor fraction.