Table 6.

Comparison of WT and APP mice on maze performance at four ages. Excludes any mice discontinued for poor swimming during a test series. T4 error is the number of errors during the last learning trial averaged across sessions. T5 error is the number of errors on a retention trial conducted 30 min after original learning averaged across sessions. Sec/error gives a measure of error rate averaged across all trials, since trial length varied.

	Timepoint
	4.5 months	7.5 months	10.5 months	15 months
T4 err APP	3.9±0.2^a ^*	3.4±0.2^*	3.1±0.2^***	3.2±0.9
WT	3.0±0.4	2.4±0.4	1.9±0.3	2.3±0.4

T5 err APP	4.3±0.2^**	3.6±0.2^***	2.9±0.2^***	2.9±0.2
WT	3.0±0.5	2.3±0.4	1.4±0.3	1.3±0.3

sec/error APP	6.4±0.2^*	6.1±0.2^***	6.2±0.2^**	6.2 0.2^****
Wt	7.3±0.4	7.6±0.3	7.0±0.3	7.9 0.2

mean ± SEM

p<.05

^**

p<.02

^***

p<.01

^****

p<.0001 ANOVA