Figure 7.

Chaperone modules in an experimental folding pathway model. (A) A generally accepted experimental model for chaperone-mediated protein folding pathway in the cell cytoplasm (Young et al, 2004). (B) 5 single pathway modules derived from the model. (C) Four multiple pathway modules derived from the model. (D) A list of the 19 new modules predicted to be present in the experimental model on the basis of our data. In (B), (C), and (D), the chaperones in each module are ordered from left to right on the basis of the model in (A).