Table 2.
Measures of glucose regulation in PCOS brothers and control men
| Brothers (n=19a) | Control (n=19) | P-Value | |
|---|---|---|---|
| AIRg (μU/ml. Min)b | 468 [285, 1200] | 569 [319, 892] | 1.00 |
| SI [×10−4 min−1/(μU/ml)]c | 4.5 [1.7, 7.4] | 5.2 [4.0, 7.7] | 0.47 |
| DI | 2540 [1080, 3172] | 2901 [2096, 4487] | 0.009 |
| SG (10−2/min) | 2.4 [1.9, 2.7] | 2.0 [1.8, 2.2] | 0.02 |
| Peak insulin after glucose infusion (μU/ml)b | 89 [51, 225] | 116 [64, 171] | 0.83 |
| Peak insulin after tolbutamide (μU/ml)b | 153 [84, 296] | 161 [104, 297] | 0.95 |
| KG (min−1) | 2.16 [1.73, 3.01] | 2.16 [1.55, 3.01] | 0.72 |
Values are the median [25%, 75% interquartile range]; P-value by Wilcoxon signed ranks test;
a
Multiple brothers and control men for a single family are averaged to yield one mean value per family;
b
to convert to picomoles/l, multiply by 7.175;
c
to convert to 10−5 per minute per picomoles/l, multiply by 1.67.