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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Psychopharmacology (Berl). 2009 Feb 20;204(3):477–488. doi: 10.1007/s00213-009-1481-z

Figure 3.

Figure 3

Effects of yohimbine (left panels) and RS-79948 (right panels) on alcohol self-administration (A, B) and reinstatement (C, D). Self-administration: Data are expressed as the number (±sem) of alcohol deliveries (A) and intake (B). In A and B, open bars represent vehicle, light grey the low dose, medium grey, the medium dose and black bars the high dose of respectively, yohimbine or RS-79948. The left and right y-axes of A and B represent alcohol deliveries and intake, respectively. * Significant differences from the vehicle condition (p<0.05). † Significant differences from the 0.2 mg/kg RS-79948 dose (p<0.05). Reinstatement: Data are expressed as the number of responses (±sem) on the inactive and previously active levers. Open bars, inactive lever; closed bars, active lever. * significant differences from the vehicle condition (p<0.05).n= 10-14 rats/drug.