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. 2009 Apr 20;113(25):6304–6314. doi: 10.1182/blood-2008-10-186601

Figure 2.

Figure 2

Changes in T-cell counts after rhIL-7 administration. (A) CD4+ and CD8+ T-cell counts decreased significantly on days 1 and 2 and increased significantly on day 14 after the rhIL-7 dose. ● represents placebo participants (Inline graphic) and ▲ represents rhIL-7 participants (Inline graphic). (B) CD4+ and CD8+ T-cell changes from baseline according to rhIL-7 dose group. ● represents placebo participants (Inline graphic) and rhIL-7 participants are represented by ▲ (3 μg/kg), ■ (10 μg/kg), ♦ (30 μg/kg), and X (60 μg/kg). (C) Central memory CD4+ and CD8+ T cells decreased significantly on day 1 and increased significantly on day 14 and day 28 (CD8+ T cells) after a single rhIL-7 administration. ● represents placebo participants (Inline graphic) and ▲ represents rhIL-7 participants (Inline graphic).