Table 2.
Stratum | Day 0 | Day 1 | Day 4 | Day 14 | Day 28 | Day 56 | Day 70 | |
---|---|---|---|---|---|---|---|---|
Placebo | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | < 50 | |
rhIL-7 3 μg/kg | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | ||
rhIL-7 3 μg/kg | 1 | 207* | < 50 | < 50 | 433 | < 50 | ||
rhIL-7 3 μg/kg | 1 | < 50 | < 50 | < 50 | ||||
Placebo† | 2 | 306 | 206 | 209 | 421 | 963 | 627 | |
rhIL-7 3 μg/kg† | 2 | 87 | < 50 | < 50 | < 50 | 52 | ||
rhIL-7 3 μg/kg† | 2 | 1300 | 2640 | 1440 | 1660 | |||
rhIL-7 3 μg/kg† | 2 | 9665 | 21200 | 17100 | 49 | 4220 | ||
Placebo | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | ||
rhIL-7 10 μg/kg | 1 | < 50 | < 50 | 73 | < 50 | < 50 | ||
rhIL-7 10 μg/kg | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | ||
rhIL-7 10 μg/kg | 1 | < 50 | < 50 | 125 | 101 | 96 | ||
Placebo† | 2 | 1038 | 946 | 673 | 843 | 1590 | ||
rhIL-7 10 μg/kg† | 2 | < 50 | < 50 | 56 | 141 | < 50 | ||
rhIL-7 10 μg/kg† | 2 | 2615 | 1690 | 1080 | 435 | 435 | ||
rhIL-7 10 μg/kg† | 2 | 2184.5 | < 50 | < 50 | < 50 | < 50 | ||
Placebo | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | ||
rhIL-7 30 μg/kg | 1 | < 50 | < 50 | 83 | < 50 | < 50 | < 50 | |
rhIL-7 30 μg/kg | 1 | < 50 | < 50 | 79 | < 50 | < 50 | ||
rhIL-7 30 μg/kg | 1 | < 50 | < 50 | 154 | < 50 | 61 | < 50 | |
Placebo | 1 | < 50 | < 50 | <50 | < 50 | < 50 | ||
rhIL-7 60 μg/kg | 1 | < 50 | < 50 | < 50 | < 50 | < 50 | ||
rhIL-7 60 μg/kg | 1 | < 50 | < 50 | 66 | < 50 | < 50 | ||
rhIL-7 60 μg/kg | 1 | < 50 | < 50 | < 50 | < 50 | < 50 |
Numbers in bold represent plasma HIV-RNA levels above detection from subjects with HIV-RNA less than 50 copies/mL on day 0.
Stratum 1 subject with HIV-RNA less than 50 copies/mL at screening but 207 copies/mL on day 0.
Participants with HIV-RNA above the limit of detection at screening (stratum 2).