Table 2.
Down-regulated lysosomal genes in response to viable HIV-1
| Acc no. | Symbol | Name | FC | B |
|---|---|---|---|---|
| R08817 | ACP5 | Acid phosphatase 5, tartrate resistant | −3.0 | 4.4 |
| AA644088 | CTSC | Cathepsin C | −1.8 | 0.2 |
| AA457725 | GABARAP | GABA(A) receptor-associated protein | −1.5 | 0.0 |
| AA418683 | HPS1 | Hermansky-Pudlak syndrome 1 | −1.6 | 0.3 |
| AA630104 | LIPA | Lipase A, lysosomal acid, cholesterol esterase | −1.9 | 0.3 |
| W72651 | LYPLA3 | Lysophospholipase 3 (lysosomal phospholipase A2) | −1.8 | 0.3 |
| AW025732 | NCF2 | Neutrophil cytosolic factor 2 | −2.2 | 1.8 |
| AA630449 | NPC2 | Niemann-Pick disease, type C2 | −1.5 | 0.7 |
| AI954240 | SGSH | N-sulfoglucosamine sulfohydrolase (sulfamidase) | −2.0 | 5.4 |
| AA063637 | PPT1 | Palmitoyl-protein thioesterase 1 | −1.4 | −0.3 |
The table shows the GenBank43 accession number symbol and name, the fold change increase in its expression (FC), and B value (B), for all lysosomal genes down-regulated in MDDC response to treatment with viable HIV-1 for 48 hours. No lysosomal genes were down-regulated in response to treatment with AT-2–inactivated HIV-1.