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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Biochim Biophys Acta. 2008 Nov 21;1787(5):290–295. doi: 10.1016/j.bbabio.2008.11.005

Fig. 4. Expression in Schneider cells of Drosophila mtDNA helicases carrying mutations in the putative TOPRIM fold and RNAP basic domain.

Fig. 4

Schneider cells containing no plasmid (control) or carrying pMt/K193A/Hy (K193A), pMt/D232A/Hy ( D232A ), pMt/D277A/Hy (D277A), pMt/F267A/Hy (F267A), or pMt/W273A/Hy (W273A) were cultured for 14 days in the absence or presence of 0.2 mM CuSO4. A, Immunoblot analysis of d-mtDNA helicase and d-ATPase β was carried out as described in the legend to Fig. 2. B, mtDNA abundance was determined as described in the legend to Fig. 2.