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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Circ Res. 2008 Jul 3;103(3):279–288. doi: 10.1161/CIRCRESAHA.108.175919

Figure 1.

Figure 1

Effects of CGP-37157 on [Ca2+]m accumulation and NADH production. Rhod-2 and NADH fluorescence were recorded simultaneously in patch-clamped myocytes with or without treatment of CGP-37157. In the presence of 100 nM isoproterenol, cells were recorded at rest, during 4-Hz stimulation (gray frame), and at rest again for recovery. Pipette solutions contained either 5 or 15 mmol/L Na+ as indicated. A–D, Recording of rhod-2 and NADH without CGP-37157 in cells with 5 mmol/L Na+ (A, C, n=11) and 15 Na+ (B, D, n=14). E–H, Effects of treatment with CGP-37157 on rhod2 and NADH signals in cells with 5 mmol/L Na+ (E, G, n=14) and 15 mmol/L Na+ (F, H, n=8).