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. Author manuscript; available in PMC: 2010 May 6.
Published in final edited form as: J Am Chem Soc. 2009 May 6;131(17):6088–6089. doi: 10.1021/ja901876z

Figure 1.

Figure 1

(Top) A sandwich immunoassay is performed by exposing antibody-functionalized microbeads to three solutions: (1) an antigen containing sample, (2) biotinylated detection antibodies, and (3) streptavidin modified with a Ru(bpy)3 2+ complex (SA-Ru). The beads are housed in microwells created from an etched gold-coated fiber-optic bundle. The gold coated fiber bundle acts as the working electrode (WE) for ECL. CE and RE refer to counter electrode and reference electrode.