Figure 8. Overexpression of HtrA2 can rescue PINK1 climbing defect.
Compared to heterozygous controls, PINK1 mutants have reduced climbing ability, which is suppressed by overexpression of HtrA2 under the control of the actin5c promoter. Bars show mean and standard error, n>50. Significance was established using a Kruskal Wallis test and Dunn’s comparison (***, p<0.0001; *, p<0.01).