Table 1.
XRCC1 genotype | N | Good response [N (%)] |
Poor response [N (%)] |
OR | 95%CI |
Codon 194 Arg/Arg |
34 | 28 (82.35) | 6 (17.65) | ||
Arg/Trp | 24 | 24 (100) | 0 (0) | ||
Trp/Trp | 12 | 8 (66.67) | 4 (33.33) | 2.333 | 0.52~10.35 |
Arg/Trp+ Trp/Trp | 36 | 32 (88.89) | 4 (11.11) | 0.583* | 0.14~2.28 |
Codon 399 Arg/Arg |
44 | 40(90.90) | 4 (9.10) | ||
Arg/Gln | 2 | 0 (0) | 2 (100) | ||
Gln/Gln | 24 | 20 (83.33) | 4 (16.67) | 2.000 | 0.452 ~8.842 |
Arg/Gln+ Gln/Gln | 26 | 20 (76.92) | 6 (23.08) | 3.254** | 1.708 ~ 14.951 |
Good response: CR+PR; Poor response: SD+PD; OR: odds ratio
*: Arg/Trp+Trp/Trp vs Arg/Arg; **: Arg/Gln+Gln/Gln vs Arg/Arg