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. 2009 Jun 29;9:49. doi: 10.1186/1471-230X-9-49

Table 2.

Prevalence and Incidence of Celiac Disease (CD) and Seropositivity for IgA Class Tissue Transglutaminase (tTGA) and Endomysial (EmA) Antibodies in Patients Aged Over 55 Years.

Year, total population Procedure Number clinically detected tTGA positive in screening EmA positive in screening Biopsy-proven cases in screening Overall frequency of biopsy proven CD Patients with CD and tTGA seropositive individuals
2002, 2815 Serum sampling
2004, 2815 Recording of detected CD. First serologic analysis 25 48 43 35 60 69a
2005, 2216 Recording of detected CD. Second serologic screening 1 6 4 5b 6 7
Overall prevalence, N = 2815 0.92% (26/2815) 1.92%
(54/2815)
1.70% (47/2815) 1.42%
(40/2815)
2.34%
(66/2815)
2.70%
(76/2815)
95% confidence intervals 0.57–1.27% 1.41–2.43% 1.22–2.18% 0.98–1.86% 1.78–2.90% 2.10–3.30%

a Four seropositive were found to have celiac disease between 2002–2004

bThe incidence of celiac disease 2002–2005 was 0.23% (5/2216)