Table 3.
Etoposide Loading in stPCL-PEG32 and stPLA-PEG32 Polymers
| polymer | polymer conc. (mg/mL) | etoposide (mg/mL)a | loading in polymer (w/w %) |
|---|---|---|---|
| stPCL-PEG32 | 2.4 | 0.12 | 5.0 |
| 3.0 | 0.23 | 7.8 | |
| 5.0 | 0.29 | 5.9 | |
| 8.0 | 0.31 | 3.9 | |
| 15 | 0.50 | 3.4 | |
| stPLA-PEG32 | 2.4 | 0.05 | 2.2 |
| 3.0 | 0.13 | 4.3 | |
| 5.0 | 0.16 | 3.2 | |
| 8.0 | 0.19 | 2.4 | |
| 15 | 0.43 | 2.8 |
The etoposide concentration values are within ± 3%.