Table 2.

DNA damage of nuclear genes in cerebral cortex after forebrain ischemia

	Pixel values × 10−3		Zero class R=(+Fpg/−Fpg)	FPGSS frequency (−ln R)
	+Fpg protein	−Fpg protein
Actin genes
Normal (N)	113	86	≥1	0
Sham operated (S)	110	91	≥1	0
Ischemic samples with reperfusion of
0 min	87	118	0.74	0.3
2 min	87	106	0.82	0.2
10 min	91	117	0.78	0.2
20 min	40	139	0.29	1.2
240 min	132	119	0.94	0.1
360 min	145	152	0.95	0.1
DNA polymerase-β
Normal (N)	415	324	≥1	0
Sham operated (S)	487	399	≥1	0
Ischemic samples with reperfusion of
0 min	191	269	0.71	0.3
2 min	224	260	0.86	0.2
10 min	162	243	0.67	0.4
20 min	111	178	0.62	0.5
240 min	81	94	0.86	0.2
360 min	159	170	0.94	0.1

The pixel values are the average of four pixel readings on the same blot presented in Figure 9. FPGSS frequency was calculated according to Mellon et al. (1987).