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. 2009 Apr 8;96(7):2808–2822. doi: 10.1016/j.bpj.2008.12.3914

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© 2009 by the Biophysical Society.

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Closing direction of twisting mode in EcoO109I and EcoRI. (A and B) Side view of DNA-bound form of EcoO109I and EcoRI, respectively, colored according to common structural motif in the catalytic domain (blue) and other parts (green) in one subunit. Counterpart subunit is shown in transparent representation. DNA molecules (red) are shown, as minor groove faces upward. Yellow arrows represent closing direction of the twisting mode in EcoO109I and EcoRI, i.e., counterclockwise rotation in EcoO109I and clockwise rotation in EcoRI.