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. 2009 Apr 8;96(7):2624–2636. doi: 10.1016/j.bpj.2009.01.018

Table 1.

Known representative parameter values for virus spikes, receptors, and coreceptors, and their article references

Quantity HIV-1 HSV-1
Radius R 0.05 μm (52) 0.1 μm (53)
Spikes/virus 8–14 (55,56) 235–480 gD (54)
∼700 total (44)
Receptor KD ≈ 5 nM (57)
Binding ΔH ≈ −100 kBT (57)
Coreceptor KD ≈ 4 nM (58)
Binding ΔH ≈ −300 kBT (59)
Receptor diff. 0.044 μm2/s (60)
Const. Dr
Coreceptor diff. 0.05 μm2/s (60)
Const. Dc
Host cell radius T-cell Epithelial cell
4 μm (61) 5 μm (62)
Cell receptor 300–3000 6–9 × 106
Density CD4/μm2 (63) HS/μm2 (64)
Cell coreceptor 60 CCR5/μm2 (63)
Density