Table 2.

Conditions for 1), survival to fully wrapped state after activation; 2), endocytosis being faster than fusion; and 3), reaching the activated state before fusion

	Condition 1		Condition 2		Condition 3
	Fast or slow def.	Survival to fully wrapped state	Fast or slow def.	Endocytosis faster than fusion	Fast or slow def.	Survival to activated state
Fast coreceptor binding	$\frac{q_1^{\mathrm{a}}}{p_1^{\mathrm{a}}}\mathrm{\gtrsim }1$	$\frac{k_{\mathrm{f}}M}{p_1^{\mathrm{a}}}\ll 1$	$\frac{q_1^{\mathrm{a}}}{p_1^{\mathrm{a}}}\mathrm{\gtrsim }1$	ke ≫ Nkf	qi1τa ≳ 1	τakf ≪ 1
Slow coreceptor binding	$\frac{1}{N}\ll \frac{q_1^{\mathrm{a}}}{p_1^{\mathrm{a}}}\ll 1$	$\left(\frac{k_{\mathrm{f}}M}{p_1^{\mathrm{a}}}\right)\left(\frac{q_1^{\mathrm{a}}}{p_1^{\mathrm{a}}}\right)\ll 1$	$\frac{q_1^{\mathrm{a}}}{p_1^{\mathrm{a}}}\ll 1,$q1aN ≪ kf	ke ≫ Nq1a	q1iτa ≪ 1	τa2kfqi1 ≪ 1