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Wiring diagrams for processes regulating p53 and those regulated by p53. (A) E2F1 enhances apoptosis. (B) DYRK2 transforms p53 helper to p53 killer. (C) p53 and p73 induce apoptosis. (D) p53 inactivates E2F1. Notations are as in Fig. 2. See text for details.
