Table 1.

McDonald–Kreitman tests of neutrality

	Fixed		Polymorphic		G
	Syn.	Rep.	Syn.	Rep.
Complete coding region
mel/sim	27	28	32	17	2.79
mel/sim/yak	107	123	53	31	6.83**
N-terminal region (219 codons)
mel/sim	15	7	11	7	0.22
mel/sim/yak	57	69	24	17	2.20
Loop domains (157 codons)
mel/sim	9	16	12	6	4.00*
mel/sim/yak	27	40	17	7	6.74**
Transmembrane domains (139 codons)
mel/sim	3	5	9	4	2.05
mel/sim/yak	23	14	12	7	0.005

*, P < 0.05; **, P < 0.01.