Table 1.
Sample | Height (nm) | Actual width (nm) |
---|---|---|
Monomer (0 h) | 3.0 ± 0.2 | 3.8 ± 0.8 |
Oligomer (3 h) | 3.9 ± 0.1 | 9.5 ± 1.0 |
Protofibril (10.5 h) | 3.9 ± 0.3 | 9.5 ± 1.7 |
Protofibril (55 h) | 3.9 ± 0.2 | 9.6 ± 1.0 |
Mature Fibril (100 h) | 6.0 ± 0.2 | 13.9 ± 1.0 |
Averages of heights and actual widths for various intermediate aggregates formed during HEWL fibrillogenesis were obtained using AFM.