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Root mean-square deviation (RMSD) of Cα atoms of (A) DNA-free (orange) and G:T-bound MSH2-MSH6 (dark green); (B) only clamp and; (C) only lever domain of DNA-free MSH6 (orange), DNA-free MSH2 (red), G:T-bound MSH6 (dark green) and G:T-bound MSH2 (light green).
