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. Author manuscript; available in PMC: 2009 Jul 16.
Published in final edited form as: Neuron. 1998 Aug;21(2):325–334. doi: 10.1016/s0896-6273(00)80542-5

Figure 6. TrkB- and TrkC-Positive Cells Do Not Die in TrkC- and TrkB-Deficient DRGs, Respectively.

Figure 6

(A–C) Confocal microscopy of lumbar DRGs (middle portion of the ganglion) in a wild-type E11 embryo stained with anti-TrkB ([A], green) and anti-TrkC ([B], red) shows in a combined image that some cells express both receptors (C). Section through a lumbar DRG of a TrkC-deficient E11 embryo stained with antibodies to TrkB (D). Notice that, in spite of the presence of numerous pyknotic figures (arrows), none are positive for TrkB. Section through a lumbar DRG of a TrkB-deficient E11 embryo was stained with antibodies to TrkC (E). Only a few pyknotic profiles are observed (arrows), none of which are positive for TrkC. Scale bar, 20 μm.