Table 1.

Morphometric and LV measurements (14 days post-MI)

Parameters	WT-sham	KO-sham	WT-MI	KO-MI	WT-MI+PD	KO-MI+PD	P value
Body weight, g	29.52±2.52	35.20±2.42	27.90±2.42	31.91±3.73	28.17±3.17	28.74±5.88	-
Infarct size, %LV circumference	-	-	53.02±1.29	50.49±2.31	52.36±2.08	51.35±2.81	-
Heart/Body weight ratio, mg/g	5.51±0.19	5.88±0.28	9.57±0.83* †	7.70±1.11*	9.51±0.43	9.57±1.83#	*<0.01; †<0.05; #<0.05
LV Fibrosis, % pixel	0.18±0.03	0.17±0.01	22.42±3.20* †	9.80±0.99*	20.69±1.14	18.39±2.39#	*<0.001; †<0.005; #<0.01

Values are mean±SE; n=5 in each group

^*comparison between sham and MI within genotype

^†comparison between MI groups

^#comparison between MI+PD and MI within genotype