Table II.
Frequencies of p21-positive and/or BrdU-negative cells within the APB-positive populations after a 4-d induction of p53 and a 24-h pulse of BrdU
| Cell lines (treatmenta) | Total APB+ countedb | p21+ (%) | BrdU− (%) | p21+ and BrdU− (%) |
| C7 (4OHT) | 150 | 132 (88.0) | 129 (86.0) | 122 (81.3) |
| C8 (4OHT) | 127 | 105 (82.7) | 106 (83.5) | 94 (74.0) |
| IIICF-T/B3(SV40T-siRNA) | 153 | 128 (83.7) | 131 (85.6) | 115 (75.2) |
a
Cells were treated with 1 µM 4OHT or 10 nM SV40T siRNA for 4 d, and BrdU was added 24 h before the end of treatment.
b
Only cells that were APB positive were examined for BrdU and p21.