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. 2009 Jun 15;185(6):1111–1125. doi: 10.1083/jcb.200901029

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© 2009 Warner and Longmore

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 9. — Working model for Rho function in remodeling, formed epithelia. Rho regulates apical cell tension and AJs independently. Rho sustains apical cell tension mainly through Rok, but Dia can cooperate with Rok for this role. Rho maintains formed AJs by inhibiting DE-cadherin endocytosis, possibly by inhibiting Cdc42/Par6 activity.