Figure 2. Cells spread on “soft” polyacrylamide only if coated with a continuous fibrin network.

Spread area of fibroblasts (A) or hMSCs (B) cultured for 18 hours on 100 Pa polyacrylamide gels coated with either fibrinogen monomers, fibrin monomers, thin fibers, thick fibers, a network of thin fibers or a network of thick fibers. Reported as mean±SE, n = 3, at least 50 cells per group.