Figure 7. Fibrinogen concentration and distance to the nearest cell both regulate cell shape and patterning.
The degree of alignment (A), projected cell area (B), orientation angle (C) and circularity (D) of neighboring hMSCs were analyzed as a function of distance to the nearest cell on four substrates: 1, 2, and 8 mg/ml fibrin as well as 16 kPa fibrinogen coated polyacrylamide. Reported as mean±SE, n = 3, at least 10 cells per group.