Table 2.

Sensitivity Analysis showing the Sensitivity, Specificity, and Positive Predictive Value of a Claims-Based Algorithm to Correctly Classify Incident Vertebral Compression Fractures, with Variations Based on Re-Classifying the Fractures with Uncertain Acuity

	Se*(95% CI)	Sp*(95% CI)	PPV (95% CI)
VCF diagnosis on an E/M claim from a physician, preceded by spinal imaging within the previous 10 days; OR VCF diagnosis on a hospitalization claim, primary diagnosis**	56 (43−68)	69 (58−80)	61 (49−74)
All UTD fractures excluded
As above	51 (42−60)	69 (58−80)	74 (64−83)
All UTD fractures classified as new
As above	56 (43−68)	62 (53−70)	42 (31−52)
All UTD fractures classified as old

Se = Sensitivity; Sp = Specificity; PPV = Positive Predictive Value; CI = Confidence Interval UTD = Unable to Determine, indicating that a VCF was confirmed but could not be classified as new or old (n =58)

^*compared to a case finding procedure that accepted any VCF diagnosis on any type of medical claim

^**same results as shown in the last row of Table 1