Table 6.
Fatty acid concentrations in heart, testis, and adipose at 15 week deprivation
| Fatty acid | Heart |
Testis |
Epididymal adipose tissue |
|||
|---|---|---|---|---|---|---|
| Adequate |
Deficient |
Adequate |
Deficient |
Adequate |
Deficient |
|
| nmol/g heart | nmol/g heart | nmol/g testis | nmol/g testis | nmol/g adipose tissue | nmol/g adipose tissue | |
| n-6 PUFA | ||||||
| 18:2 | 16632 ± 999 | 9249 ± 1274*** (−44%) | 6102 ± 1868 | 1763 ± 734 *** (−71%) | 56143 ± 16376 | 5265 ± 907*** (−91%) |
| 18:3 | 102 ± 45 | 58 ± 6* | 51 ± 9 | 37 ± 10** | 299 ± 87 | 100 ± 39*** |
| 20:3 | 373 ± 49 | 770 ± 49*** | 426 ± 41 | 500 ± 73 ** | 388 ± 107 | 81 ± 38 *** |
| 20:4 | 13434 ± 503 | 8208 ± 715*** (−39%) | 5481 ± 606 | 4117 ± 571 *** (−25%) | 1709 ± 399 | 365 ± 63 *** (−79%) |
| 22:4 | 717 ± 70 | 102 ± 34*** | 843 ± 82 | 493±78 *** (−42%) | 515 ± 117 | 314 ± 130 *** |
| 22:5 | 478 ± 63 | 55 ± 22*** | 5899 ± 804 | 4320 ± 616 *** | 74 ± 14 | ND |
| Total | 31737 ± 867 | 18442 ± 2039*** (−42%) | 18802 ± 1719 | 11231 ± 1591 *** (−40%) | 59127 ± 16920 | 6124 ± 1025*** (−90%) |
| n-3 PUFA | ||||||
| 18:3 | 307 ± 55 | 647 ± 82*** | 528 ± 218 | 498 ± 247 | 6619 ± 1844 | 5272 ± 892 |
| 20:5 | 122 ± 80 | 1486 ± 202*** (+1118%) | 57 ± 14 | 291 ± 43 *** (+411%) | 285 ± 257 | 253 ± 256 |
| 22:5 | 1779 ± 177 | 2308 ± 150*** | 133 ± 37 | 219 ± 55 *** | 374 ± 92 | 276 ± 55* |
| 22:6 | 7555 ± 446 | 9337 ± 337*** (+24%) | 496 ± 49 | 1299 ± 163 *** (+162%) | 518 ± 169 | 634 ± 296 |
| Total | 9762 ± 643 | 13778 ± 482*** (+41%) | 1213 ± 306 | 2307 ± 373*** (+90%) | 7795 ± 1947 | 6435 ± 1213 |
| Others | ||||||
| 16:0 | 9702 ± 572 | 10235 ± 2025 | 14999 ± 1619 | 15380 ± 2458 | 62611 ± 14275 | 66700 ± 10380 |
| 16:1n-7 | 777 ± 176 | 2142 ± 510*** | 2795 ± 928 | 3588 ± 1778 | 19703 ± 4206 | 30617 ± 4409 *** |
| 18:0 | 16406 ± 624 | 15841 ± 1022 | 3111 ± 287 | 3035 ± 360 | 7769 ± 1964 | 6507 ± 1115 |
| 18:1n-9 | 3897 ± 611 | 8329 ± 2843*** | 7863 ± 1705 | 10250 ± 2929 * | 40315 ± 9406 | 54807 ± 9115** |
| 18:1n-7 | 2868 ± 152 | 3321 ± 204*** | 1533 ± 278 | 1853 ± 188 ** | 12384 ± 2860 | 15010 ± 2603 * |
| 20:3n-9 | 58 ± 23 | 524 ± 39*** | 51 ± 9 | 234 ± 30 *** | 167 ± 47 | 185 ± 37 |
| Total saturated | 26107 ± 974 | 26076 ± 2090 | 18109 ± 1825 | 18414 ± 2739 | 70380 ± 16210 | 73207 ± 11476 |
| Total mono | 5133 ± 1205 | 12962 ± 3042*** (+153%) | 12191 ± 2428 | 15691 ± 4814 * (+29%) | 72401 ± 16337 | 100435 ± 15866** (+39%) |
| Total | 73539 ± 4129 | 70257 ± 6461 | 50366 ± 5955 | 47876 ± 8072 | 209872 ± 50977 | 186386 ± 29260 |
| Ratio of n-6/n-3 | 3.3 | 1.3 | 16 | 4.8 | 7.5 | 1.0 |
| FA composition (% of Total FA) | ||||||
| n-6 PUFA | 43% | 26% | 37% | 23% | 28% | 3.2% |
| n-3 PUFA | 13% | 20% | 2.4% | 4.8% | 3.7% | 3.5% |
| Total saturated | 36% | 37% | 36% | 38% | 34% | 39% |
| Total monounsaturated | 8% | 18% | 24% | 33% | 34% | 54% |
| 20:3n-9 | 0.08% | 0.7% | 0.1% | 0.5% | 0.08% | 0.1% |
Values are mean ± SD (n=10 for both groups).
*
p<0.05
**
p<0.01
***
p<0.001, differs significantly from mean in adequate group.
ND, not detected.