FIGURE 3.
In vivo induction of Cre-activated β-galactosidase activity in the F1 rtTA/Cre-R26R mice. Doxycycline (0.4 mg/g body weight) was fed to mice on P3, -4, -5, -10, or -25 by gavage for 2 days. Five days after induction was initiated, the β-galactosidase assay was performed. No dox: P21 control (rtTA-Cre/R26R) mice without doxycycline induction. Each data point was derived from at least eight retinas. The strongest Cre-activated β-galactosidase activity was observed with induction at P4.
