Fig. 4.

Overall mammary gland morphology is compromised in Zip3-null mice. Representative images of mammary gland from wild-type (A) and Zip3-null (B) mice during early lactation stained with hematoxylin and eosin are shown. Magnification, ×20. Four points to note are the greater overall density (boxes), structured morphometric organization, and the well-defined ductal branching (d) observed in mammary gland from wild-type mice. In contrast, note the distinct and loose association of alveoli structures (arrows) in mammary gland from Zip3-null mice.