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Chromosomal localization of murine α1 and β1 sGC genes. DNA from BAC clones containing genomic regions of α1 and β1 sGC genes was labeled with digoxigenin dUTP and hybridized to normal metaphase chromosomes derived from mouse embryo fibroblast cells (for details see Materials and Methods). Cohybridization of α1 sGC and β1 sGC probe with a probe specific for telomeric region on chromosome 3 is shown on A and B, respectively. Arrows indicate the sites of specific hybridizations.
