Table 1.
Exon-intron splice junctions of the α1 and β1 sGC genes
| Splice donor* | Size of intron, kb | Splice acceptor | |
|---|---|---|---|
| α1 sGC | |||
| Intron 1 | cat−103g/GTGGGTTCGCTCAGC | >2.0 | TCCACTGCTCATAG/gt gct |
| Intron 2 | cca85gag/GTGAGTGTTCTCCC | 5.5 | TCTTTTTCTTTCCAG/tgt gag |
| Intron 3 | aac106ag/GTAAGCTAAGTTACC | 2.2 | TTAATTATTCCCAG/g aaa |
| Intron 4 | gca126g/GTAATAAATAAAACT | 1.9 | CTGTGTGCTTGCAG/gtg ccc |
| Intron 5 | tca362agg/GTAAGGAAAATGTAA | 3.0 | CCTTTCCTTTGCAG/gtt atg |
| Intron 6 | tac524aag/GTAGGGAAGGTGGAA | 4.2 | TATATTGTATCTAG/gtg gag |
| Intron 7 | atc572aag/GTA AGGCCGTGACTT | 4.4 | TGTTTTGCCTTCAG/atg cga |
| Intron 8 | tac624ag/GTATGGATGGCACTA | 2.8 | TAAATTGTTCTCAG/g tta |
| β1 sGC | |||
| Intron 1 | acc1atg/GTGAGTGCTGTCAG | 0.5 | TCTCTGCCCTTCAG/tac ggt |
| Intron 2 | atc26aa/GTAAGTGAACAGCC | 2.5 | TCCATTTTCTTTCAG/a aaa |
| Intron 3 | ctc60a/GTAGGTTGAAAAC | 2.4 | CATCTACAAAACAG/ac ctc |
| Intron 4 | tttg98cag/GTGAGATGTTCGAG | 0.8 | CTGCTGCACTACAG/aac ctc |
| Intron 5 | atg164aag/GTAGTGTTCACCCG | 1.1 | CCATTGACATCTAG/gtg att |
| Intron 6 | ccc241cag/GTAAAATGCACAG | 1.1 | TTTCTGTGTCTTAG/ctc cag |
| Intron 7 | agc280aag/GTAAGCAAGAACC | 1.0 | CTTTCCTGTTTAAG/gaa ggg |
| Intron 8 | cca325ag/GTAACAACTTTTAA | 3.0 | CTCTGTGTGACAG/t gtg |
| Intron 9 | gac391ac/GTAAGCAAGGGAG | 1.5 | CTAATTCCCACAG/a ttg |
| Intron 10 | tac470aag/GCAAGTCTTCATGG | 2.5 | TGTGTCACCCTAG/gtg gaa |
| Intron 11 | gtt517cag/GTGAGTAAATAAAT | 0.4 | CTTTGCTTCTGCAG/ata aca |
| Intron 12 | tac569ag/GTGAGGAGGGAAAT | 0.3 | CTCATGACTTTCAG/g tgt |
| Intron 13 | acg611gag/GTATGGCTCATTAG | 1.1 | TCGACCCATTTAAG/gaa aca |
*
The positions of codons at which the introns interrupt the coding sequence are indicated, except for the first intron of α1 sGC gene, where it indicates the base pairs upstream of the start codon.