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RBF responses to endothelin-1 (ET-1) injected intravenously in WT and CD38−/− mice. A and B: typical tracings of RBF (black circles) and MAP (gray circles) responses to ET-1 injection (7.5 ng) in WT (A) and CD38−/− mice (B). C: average RBF response to ET-1. *P < 0.05 compared with WT, n ≥ 8.
