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. 2009 Apr 29;297(1):F138–F144. doi: 10.1152/ajprenal.00122.2008

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Fig. 1. — Antibodies bind specifically, and binding is prevented by fusion protein. Left: rabbit glomeruli. Right: rat glomeruli. Monoclonal antibody (mAb) 4C3 to rabbit protein tyrosine phosphatase receptor-O (PTPro) specifically binds to rabbit tissue (top left). This binding could be blocked by preincubation with the extracellular domain (ECD) fusion protein (middle left). The control mAb BB5 did not bind to rabbit sections (bottom left). mAb 1B4 to rat PTPro binds to rat tissue (top right) and was blocked following preincubation with the ECD fusion protein (middle right). mAb 4C3 did not bind to the rat sections (bottom right).