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Diagram illustrating the membrane topology of PKD1 and TRPP2. LRR-LDL, leucine-rich repeats and low-density lipoprotein homology domains; PKD, polycystic kidney disease domain; C-type lectin: C-type lectin homology domain; REJ, receptor of egg jelly; GPS, G protein-coupled receptor (GPCR) proteolytic site.
