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. 2009 Apr 22;297(1):F177–F190. doi: 10.1152/ajprenal.90422.2008

Table 2.

Effect of experimental conditions on renal TSPO expression in the cortex and medulla


Warm Ischemia for 60 min
Sham/Unif 3 h D3 D7
Cortex:
    PT (S1; S2) 0 0 +++ +
    Distal tubule +++ + ++ +++
Medulla:
    Proximal tubule (S3) 0 0 +++ +
    TAL +++ + ++ +++
    TDL + + ++ +
    CD +++ + ++ +++
    V ++ + ++ ++
Cold Ischemia for 24 h
Cortex:
    PT (S1; S2) 0 0 ++ ++
    Distal tubule +++ + ++ +++
Medulla:
    Proximal Tubule (S3) 0 0 + ++
    TAL +++ + ++ +++
    TDL + + + +
    CD +++ + ++ +++
    V ++ + ++ ++
Warm Ischemia for 60 min and Cold Ischemia for 24 h
Cortex:
    PT (S1; S2) 0 0 0 0/+
    Distal tubule +++ 0/+ + ++
Medulla:
    Proximal Tubule (S3) 0 0 0/+ +
    TAL +++ 0/+ + ++
    TDL + 0 + +
    CD +++ 0/+ + ++
    V ++ 0 + ++

TSPO, translocator protein; TAL, thick ascending limb of Henle's loop; TDL, thin descending limb of Henle's loop; CD, collecting duct; PT, proximal tubule; DT, distal tubule; V, vessels.