Fig. 2.
Nuclear and mitochondrial protein expression and mitochondrial DNA (mtDNA) copy number. A: expression of skeletal muscle citrate synthase determined by Western blot before and after CO with or without V̇o2max testing compared with porin, the loading control. B: mtDNA copy number in muscle before and after 5 daily exposures to air or CO and one V̇o2max test, or before and after CO without exercise. C and D: mitochondrial-encoded cytochrome oxidase (COX)-I (C) and ATPase-6 protein (D) relative to porin before and after CO with or without V̇o2max test. Values are means ± SD (*P < 0.05 between groups).