Fig. 1.
Phenotypic characteristics of fibroblast growth factor (FGF) receptor-3 (FGFR-3)-null (FGFR-3−/−) and wild-type (wt/wt) mice. Immunohistochemical detection of FGFR-3 expression in 14-day-old small intestine of wild-type (A) and FGFR-3−/− (B) mice shows that FGFR-3−/− mice do not express FGFR-3. C: body weight of wild-type and FGFR-3−/− (FR3−/−) mice at 0–30 days of age. D: photograph of intestines from 21-day-old FGFR-3−/− and wild-type (FR3+/+) mice showing difference in total gut length.