Fig. 2.

Crypt formation in FGFR-3^−/− and wild-type mice. A: number of crypts per cross section in hematoxylin-eosin-stained sections from proximal jejunum and ileum of 10- and 21-day-old mice. Six separate cross sections were scored for each of 5–6 mice per group, and results were averaged. B: total number of crypts in each region of small intestine in 21-day-old FGFR-3^−/− and wild-type mice. Values are means ± SE (n = 4 mice per group). *P < 0.05. **P < 0.01. †P < 0.005. Photographs of hematoxylin-eosin-stained sections of proximal jejunum from wild-type (C) and FGFR-3^−/− (D) mice show crypts undergoing fission.