Fig. 5.
Differentiation of intestinal epithelium in FGFR-3−/− and wild-type mice. A and B: expression of intestinal fatty acid-binding protein (IFABP, red fluorescence) in jejunum of a 4-day-old FGFR-3−/− mouse. A: expression of IFAPB in all villus-associated enterocytes. Magnification ×40. B: occasional cells in intervillus epithelium expressing IFABP (arrows). Magnification ×200. C: Paneth cells (arrows) in ileum of 14-day-old FGFR-3−/− mouse. Magnification ×400. D: peptide YY (PYY)-expressing cells (arrowhead) in ileum of 4-day-old FGFR-3−/− mouse. Magnification ×400. E: serotonin-containing neuroendocrine cells in jejunum (arrowheads) of 4-day-old FGFR-3−/− mouse. Magnification ×200. F: goblet cells (arrows) in jejunum of 10-day-old FGFR-3−/− mouse.